Early detection
Catch Metabolic Disease Years Before Your A1c Flags It
Why the standard blood test marks the end of a long process rather than the start of one.
Food and contaminants
Dark Chocolate Can Contain Lead: What That Means This Valentine's Day
How heavy metals get into a food sold as the healthy option, and how much of it matters.
Oral GLP-1s
Wegovy's New Weight Loss Pill: What It Changes, From A Harvard Doctor
What moving semaglutide from an injection to a tablet does and does not change about the treatment.
Matching treatment to biology
Series · 5 of 5How Modern Weight Loss Treatments Work And Who They Work Best For
Medications, endoscopic therapies and surgery act on different mechanisms; outcomes improve when the tool matches the dominant driver.
Obesity phenotypes
Series · 4 of 5Why Maintaining A Healthy Weight Isn't The Same For Everyone
Obesity is not one disease. Distinct biological phenotypes explain why the same treatment transforms one person and disappoints another.
Why the set point rises
Series · 3 of 5Why Your Weight Set Point Rises And How It Drives Weight Gain
The defended range is not fixed. Leptin and insulin resistance, sleep, stress and the microbiome all push it upward.
The defended range
Series · 2 of 5Beyond Calories: How Your Body Defends Its Weight Set Point
Weight loss reads to the body as a survival threat. Adaptive thermogenesis and hormonal feedback are why plateaus are biology, not discipline.
Hunger and fullness
Series · 1 of 5What Really Drives Hunger And Fullness: The Science Explained
The short-term signals between gut and brain that decide when a meal starts and when it stops.
Anti-nutrients
Anti-Nutrients Explained: Oxalates, Lectins And 'Toxic' Vegetables
What the compounds in plants actually do, and how much of the case against vegetables survives contact with the evidence.
The microbiome
The Microbiome's Role In Metabolism, Brain Health And Aging
What the gut's bacterial population does for metabolism and cognition, and where the evidence stops.
Microplastics
Your Plastic Water Bottle May Be Making You Gain Weight: Microplastics
How endocrine-disrupting compounds from plastics interfere with the hormonal signals that regulate weight.
Compounded GLP-1s
Is Compounded Ozempic Safe For Weight Loss? What You Need To Know
Compounded semaglutide is not the same product as the branded drug, and the difference matters.
Cost of treatment
ESG Weight-Loss Procedure More Effective And Cheaper Than Ozempic
What a procedure and a prescription each cost over time, and what each one buys.
Medication or procedure
Ozempic And Weight-Loss Procedures: Benefits, Costs And Risks
How to weigh a medication against a procedure without a winner being declared.
Obesity as disease
Obesity Is A Disease. It's Time We Treat It Like One
The case for treating obesity as a chronic condition rather than as a question of conduct.
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