Adaptive

Human metabolism in a world it was never designed for, by Dr. Chris Thompson

Your body is not broken. It is running biology built for scarcity in an environment that has changed faster than biology can. Adaptive is the long version of that argument.C-I-02

Amazon — link when listed Signed copies — pending

What is inside

The book is in four parts, the same four as the science section of this site, which is the short version of the book.

I Ancient biology in a modern world: why humans evolved to store fat, and why genomic evolution could not keep pace.
II How weight is regulated: the hypothalamus, adipose tissue as an endocrine organ, and the gut as a sensing organ in its own right.
III When regulation becomes dysregulation: metabolic inflexibility, adipose inflammation, and why diet and exercise alone so often fall short.
IV Reengineering metabolism: what surgery taught us, what medications achieve, and the therapies now being developed.